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MELBOURNE Cheap Nike Air Max Deluxe Youth UK , Aug. 2 (Xinhua) -- A "switch" in the brain thatregulates fat-burning could be a key reason as to why obese peoplestruggle to lose weight, an Australian study published on Wednesdayhas found.


The research, released by Monash University in the CellMetabolism journal, discovered that the brain usually signals thebody to begin browning fat to burn energy when insulin levels arehigh, usually after a meal.


Tony Tiganis Cheap Nike Air Max Deluxe Shoes UK , lead author of the study, said that the brain'sability to detect insulin levels and coordinate the browning of fatis controlled by a mechanism similar to a switch.


"What happens in the context of obesity is that the switch stayson all the time -- it doesn't turn off during feeding," Tiganissaid in a media release.


"As a consequence, browning is turned off all the time andenergy expenditure is decreased all the time, so when you eat Cheap Nike Air Max Deluxe Black UK , youdon't see a commensurate increase in energy expenditure and thatpromotes weight gain."


Fat-browning is the process whereby white fat, which storesenergy, turns into brown fat which burns energy.


In contrast to high insulin levels, the brain instructs the bodyto convert the brown cells back to white cells in order to conserveas much energy as possible.


The process, when functioning normally Cheap Nike Air Max Deluxe White UK , is key to preventing thebody from gaining, or losing, too much weight.


Researchers described the discovery of the process as a majormoment in the fight to better understand, and fight obesity.


"Obesity is a major and leading factor in overall disease burdenworldwide and is poised, for the first time in modern history Cheap Nike Air Max Deluxe Triple White UK , tolead to falls in overall life expectancy," Tiganis said.


"What our studies have shown is that there is a fundamentalmechanism at play that normally ensures that energy expenditure ismatched with energy intake.


"When this is defective, you put on more weight. Potentially wemay be able to rewire this mechanism to promote energy expenditureand weight loss in obese individuals. But any potential therapy isa long way off."


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